BDBM50058442 2-Ethyl-1-(3-methoxy-phenyl)-isothiourea; hydriodide::CHEMBL503085::CHEMBL553216

SMILES CCSC(N)=Nc1cccc(OC)c1

InChI Key InChIKey=QNJCDLIOQIVDBY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50058442   

TargetNitric oxide synthase, brain(Human)
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50058442(CHEMBL503085 | CHEMBL553216 | 2-Ethyl-1-(3-methoxy...)
Affinity DataKi:  560nMAssay Description:Inhibition of nNOS assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50058442(CHEMBL503085 | CHEMBL553216 | 2-Ethyl-1-(3-methoxy...)
Affinity DataKi:  560nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase in brain (nNOS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50058442(CHEMBL503085 | CHEMBL553216 | 2-Ethyl-1-(3-methoxy...)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibitory activity against human vascular endothelial nitric oxide synthase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50058442(CHEMBL503085 | CHEMBL553216 | 2-Ethyl-1-(3-methoxy...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibitory activity against human inducible nitric oxide synthase (iNOS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed