BDBM50058447 2-Ethyl-1-(4-methoxy-phenyl)-isothiourea; hydriodide::CHEMBL503073::CHEMBL545439

SMILES CCSC(N)=Nc1ccc(OC)cc1

InChI Key InChIKey=NOKUUQSEHGNKQI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50058447   

TargetNitric oxide synthase, brain(Human)
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50058447(2-Ethyl-1-(4-methoxy-phenyl)-isothiourea; hydriodi...)
Affinity DataKi:  290nMAssay Description:Inhibition of nNOS (unknown origin) assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, brain(Human)
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50058447(2-Ethyl-1-(4-methoxy-phenyl)-isothiourea; hydriodi...)
Affinity DataKi:  290nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase in brain (nNOS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, endothelial(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50058447(2-Ethyl-1-(4-methoxy-phenyl)-isothiourea; hydriodi...)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibitory activity against human vascular endothelial nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, inducible(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50058447(2-Ethyl-1-(4-methoxy-phenyl)-isothiourea; hydriodi...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibitory activity against human inducible nitric oxide synthase (iNOS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed