BDBM50058520 7-(3,4,5-Trimethoxy-phenyl)-4b,5,6,7,8,8a,9,10-octahydro-1,3,7,10-tetraaza-phenanthrene-2,4-diamine::CHEMBL299927

SMILES COc1cc(cc(OC)c1OC)N1CCC2C(CNc3nc(N)nc(N)c23)C1

InChI Key InChIKey=DUKSWTDASFETGZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50058520   

TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058520(7-(3,4,5-Trimethoxy-phenyl)-4b,5,6,7,8,8a,9,10-oct...)
Affinity DataIC50: 160nMAssay Description:Inhibitory concentration against Rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058520(7-(3,4,5-Trimethoxy-phenyl)-4b,5,6,7,8,8a,9,10-oct...)
Affinity DataIC50: 160nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058520(7-(3,4,5-Trimethoxy-phenyl)-4b,5,6,7,8,8a,9,10-oct...)
Affinity DataIC50: 290nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058520(7-(3,4,5-Trimethoxy-phenyl)-4b,5,6,7,8,8a,9,10-oct...)
Affinity DataIC50: 290nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058520(7-(3,4,5-Trimethoxy-phenyl)-4b,5,6,7,8,8a,9,10-oct...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory concentration against Pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058520(7-(3,4,5-Trimethoxy-phenyl)-4b,5,6,7,8,8a,9,10-oct...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed