BDBM50059375 5-Amino-3-(4-methoxy-phenyl)-thiazolo[3,2-a]pyrimidin-7-one::CHEMBL89472

SMILES COc1ccc(cc1)-c1csc2nc(=O)cc(N)n12

InChI Key InChIKey=MLNHYWWTTFZRTB-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50059375   

TargetAdenosine receptor A3(Human)
Chembridge

Curated by ChEMBL
LigandPNGBDBM50059375(5-Amino-3-(4-methoxy-phenyl)-thiazolo[3,2-a]pyrimi...)
Affinity DataKi:  18nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding stimulated by 20 uM 5''-N-ethyluronamidoadenosine (NECA) in membranes of HEK293 cells expressing human Adenos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Chembridge

Curated by ChEMBL
LigandPNGBDBM50059375(5-Amino-3-(4-methoxy-phenyl)-thiazolo[3,2-a]pyrimi...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]AB-MECA from human Adenosine A3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Chembridge

Curated by ChEMBL
LigandPNGBDBM50059375(5-Amino-3-(4-methoxy-phenyl)-thiazolo[3,2-a]pyrimi...)
Affinity DataKi:  18nMAssay Description:Displacement of specific [125I]AB-MECA binding at human adenosine A3 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Nutrition Research Institute

Curated by ChEMBL
LigandPNGBDBM50059375(5-Amino-3-(4-methoxy-phenyl)-thiazolo[3,2-a]pyrimi...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]DPCPX binding to human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Nutrition Research Institute

Curated by ChEMBL
LigandPNGBDBM50059375(5-Amino-3-(4-methoxy-phenyl)-thiazolo[3,2-a]pyrimi...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]CGS-21680 binding to human Adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed