BDBM50059749 3-Methyl-4-phenyl-quinoline-2-carboxylic acid benzyl-methyl-amide::CHEMBL15248

SMILES CN(Cc1ccccc1)C(=O)c1nc2ccccc2c(c1C)-c1ccccc1

InChI Key InChIKey=LMAZVQQMVXMTEY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50059749   

TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50059749(3-Methyl-4-phenyl-quinoline-2-carboxylic acid benz...)
Affinity DataIC50: 2.10nMAssay Description:In vitro binding affinity (pIC50) was tested against peripheral benzodiazepine receptor (PBR) in rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50059749(3-Methyl-4-phenyl-quinoline-2-carboxylic acid benz...)
Affinity DataIC50: 2.10nMAssay Description:In vitro displacement of [3H]PK11195 from the peripheral benzodiazepine receptor (PBR) in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50059749(3-Methyl-4-phenyl-quinoline-2-carboxylic acid benz...)
Affinity DataIC50: 2.10nMAssay Description:Test in vitro, for potential ability to displace [3H]1 from PBR in rat brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50059749(3-Methyl-4-phenyl-quinoline-2-carboxylic acid benz...)
Affinity DataIC50: 2.10nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in rat brain cortex membrane incubated for 120 mins by liquid scintillation spectrometer methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50059749(3-Methyl-4-phenyl-quinoline-2-carboxylic acid benz...)
Affinity DataIC50: 4.60nMAssay Description:Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed