BDBM50059924 4-(2,6-Diamino-9H-purin-8-yl)-2,6-dimethoxy-phenol::4-(2,6-diamino-9H-purin-8-yl)-2,6-dimethoxyphenol::CHEMBL105020

SMILES COc1cc(cc(OC)c1O)-c1nc2nc(N)nc(N)c2[nH]1

InChI Key InChIKey=TWOVCAQBEASXFN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50059924   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059924(4-(2,6-diamino-9H-purin-8-yl)-2,6-dimethoxyphenol ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059924(4-(2,6-diamino-9H-purin-8-yl)-2,6-dimethoxyphenol ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059924(4-(2,6-diamino-9H-purin-8-yl)-2,6-dimethoxyphenol ...)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059924(4-(2,6-diamino-9H-purin-8-yl)-2,6-dimethoxyphenol ...)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059924(4-(2,6-diamino-9H-purin-8-yl)-2,6-dimethoxyphenol ...)
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed