BDBM50059976 2-(3-Chloro-phenyl)-5,7-dimethyl-1H-[1,8]naphthyridin-4-one::CHEMBL51408

SMILES Cc1cc(C)c2c(O)cc(nc2n1)-c1cccc(Cl)c1

InChI Key InChIKey=NOFNRYRLTLGEFI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059976   

TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50059976(2-(3-Chloro-phenyl)-5,7-dimethyl-1H-[1,8]naphthyri...)
Affinity DataIC50:  770nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059976(2-(3-Chloro-phenyl)-5,7-dimethyl-1H-[1,8]naphthyri...)
Affinity DataIC50:  776nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed