BDBM50060279 3-(4-Dodecanoyl-1,3,5-trimethyl-1H-pyrrol-2-yl)-propionic acid::CHEMBL442012

SMILES CCCCCCCCCCCC(=O)c1c(C)c(CCC(O)=O)n(C)c1C

InChI Key InChIKey=OSPNFBMKODBJJE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50060279   

TargetCytosolic phospholipase A2(Bovine)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50060279(3-(4-Dodecanoyl-1,3,5-trimethyl-1H-pyrrol-2-yl)-pr...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of cPLA2 measuring Calcium ionophore A-23,187-induced arachidonic acid release from bovine platelets with HPLC/UV detectionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E synthase(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50060279(3-(4-Dodecanoyl-1,3,5-trimethyl-1H-pyrrol-2-yl)-pr...)
Affinity DataIC50:  800nMAssay Description:Inhibition of mPGES-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E synthase(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50060279(3-(4-Dodecanoyl-1,3,5-trimethyl-1H-pyrrol-2-yl)-pr...)
Affinity DataIC50:  670nMAssay Description:Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 20 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E synthase(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50060279(3-(4-Dodecanoyl-1,3,5-trimethyl-1H-pyrrol-2-yl)-pr...)
Affinity DataIC50:  800nMAssay Description:Inhibition of mPGES-1 in human A549 cell microsomes assessed as conversion of PGH2 into PGE2 at 0 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed