BDBM50060474 3-Methoxy-6,7-dihydro-5H-13-aza-benzo[3,4]cyclohepta[1,2-b]naphthalen-8-ylamine::CHEMBL119634

SMILES COc1ccc-2c(CCCc3c(N)c4ccccc4nc-23)c1

InChI Key InChIKey=CNACZOSGTBZLLB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50060474   

TargetSodium-dependent serotonin transporter(Rat)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060474(3-Methoxy-6,7-dihydro-5H-13-aza-benzo[3,4]cyclohep...)
Affinity DataIC50: 700nMAssay Description:Inhibition of neuronal uptake of 5 - Hydroxytryptamine in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060474(3-Methoxy-6,7-dihydro-5H-13-aza-benzo[3,4]cyclohep...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of neuronal uptake of Noradrenaline in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50060474(3-Methoxy-6,7-dihydro-5H-13-aza-benzo[3,4]cyclohep...)
Affinity DataIC50: 6.88E+4nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060474(3-Methoxy-6,7-dihydro-5H-13-aza-benzo[3,4]cyclohep...)
Affinity DataIC50: 6.88E+4nMAssay Description:In vitro inhibition of acetylcholinesterase, isolated from rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060474(3-Methoxy-6,7-dihydro-5H-13-aza-benzo[3,4]cyclohep...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of Butyrylcholinesterase from human plasma.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed