BDBM50060651 CHEMBL3394684

SMILES Cc1cc(CNC(=O)c2sc(-n3cnn(Cc4ccc(F)cc4)c3=O)nc2C)[nH]n1

InChI Key InChIKey=UACQNMPQQNWDHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50060651   

TargetAcyl-CoA desaturase 1(Mouse)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50060651BDBM50060651(CHEMBL3394684)
Affinity DataIC50: 9nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50060651BDBM50060651(CHEMBL3394684)
Affinity DataIC50: 280nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed