BDBM50061425 1-[(2R,3R)-3-(3,4-Dichloro-benzyloxy)-5-fluoro-2,3-dihydro-benzo[b]thiophen-2-ylmethyl]-1H-imidazole::CHEMBL133676

SMILES Fc1ccc2S[C@H](Cn3ccnc3)[C@H](OCc3ccc(Cl)c(Cl)c3)c2c1

InChI Key InChIKey=CAEKCKZQQBJFRR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061425   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061425(1-[(2R,3R)-3-(3,4-Dichloro-benzyloxy)-5-fluoro-2,3...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against recombinant human farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50061425(1-[(2R,3R)-3-(3,4-Dichloro-benzyloxy)-5-fluoro-2,3...)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibitory activity against Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed