BDBM50061447 2-Pyridin-4-yl-1-[4-(11H-10-thia-dibenzo[a,d]cyclohepten-5-ylidene)-piperidin-1-yl]-ethanone::CHEMBL132522

SMILES O=C(Cc1ccncc1)N1CCC(=C2c3ccccc3CSc3ccccc32)CC1

InChI Key InChIKey=PERCZJKRTYZWOX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50061447   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50061447BDBM50061447(2-Pyridin-4-yl-1-[4-(11H-10-thia-dibenzo[a,d]cyclo...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory activity against recombinant human farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed