BDBM50061488 1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-pyridin-2-yl-ethanone::CHEMBL335307

SMILES O=C(Cc1ccccn1)N1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1

InChI Key InChIKey=QIMRKAODXVWMEZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50061488   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50061488BDBM50061488(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against recombinant human farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed