BDBM50061707 (1-Aza-bicyclo[3.2.1]oct-5-yl)-[(Z)-methoxyimino]-acetonitrile::CHEMBL135645

SMILES CO\N=C(/C#N)C12CCN(C1)CCC2

InChI Key InChIKey=WJIDIDMJHVMZSA-FMIVXFBMSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50061707   

TargetMuscarinic acetylcholine receptor M4(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50061707((1-Aza-bicyclo[3.2.1]oct-5-yl)-[(Z)-methoxyimino]-...)
Affinity DataIC50:  49nMAssay Description:In vitro affinity of the compound is evaluated, usingquinuclidynyl benzylate (QNB) radioligand in human cloned Muscarinic acetylcholine receptor M4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50061707((1-Aza-bicyclo[3.2.1]oct-5-yl)-[(Z)-methoxyimino]-...)
Affinity DataIC50:  99nMAssay Description:In vitro affinity against human Muscarinic acetylcholine receptor M1 using quinuclidynyl benzylate (QNB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061707((1-Aza-bicyclo[3.2.1]oct-5-yl)-[(Z)-methoxyimino]-...)
Affinity DataIC50:  220nMAssay Description:In vitro inhibition of [3H]quinuclidinyl benzilate (QNB) binding to muscarinic receptors of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails

TargetMuscarinic acetylcholine receptor M2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50061707((1-Aza-bicyclo[3.2.1]oct-5-yl)-[(Z)-methoxyimino]-...)
Affinity DataIC50:  31nMAssay Description:In vitro affinity of the compound is evaluated, using quinuclidinyl benzilate (QNB) as radioligand in human cloned Muscarinic acetylcholine receptor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061707((1-Aza-bicyclo[3.2.1]oct-5-yl)-[(Z)-methoxyimino]-...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition of oxotremorine-M (OXO-M) binding to muscarinic receptors of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails

TargetMuscarinic acetylcholine receptor M3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50061707((1-Aza-bicyclo[3.2.1]oct-5-yl)-[(Z)-methoxyimino]-...)
Affinity DataIC50:  28nMAssay Description:In vitro affinity of the compound is evaluated, using quinuclidynyl benzylate (QNB)radioligand in human cloned Muscarinic acetylcholine receptor M3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed