BDBM50061827 CHEMBL135374::N-{8-Chloro-11-[1-(2-pyridin-4-yl-acetyl)-piperidin-4-ylidene]-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-3-yl}-methanesulfonamide

SMILES CS(=O)(=O)Nc1cnc2c(c1)CCc1cc(Cl)ccc1C2=C1CCN(C(=O)Cc2ccncc2)CC1

InChI Key InChIKey=PXXMROXQPFVFEH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50061827   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50061827BDBM50061827(N-{8-Chloro-11-[1-(2-pyridin-4-yl-acetyl)-piperidi...)
Affinity DataIC50: 4.60E+3nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed