BDBM50062311 (R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(R)-1-(3-morpholin-4-yl-propylcarbamoyl)-2-naphthalen-1-yl-ethyl]-succinamide::CHEMBL70430

SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@H](Cc1cccc2ccccc12)C(=O)NCCCN1CCOCC1

InChI Key InChIKey=UMZQUWRHZNAVMN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062311   

TargetNeutrophil collagenase(Human)
Glycomed

Curated by ChEMBL
LigandPNGBDBM50062311((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(R)-1-(3-morphol...)
Affinity DataKi:  0.300nMAssay Description:The compound was tested for its binding affinity towards neutrophil collagenase (Matrix metalloprotease-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glycomed

Curated by ChEMBL
LigandPNGBDBM50062311((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(R)-1-(3-morphol...)
Affinity DataKi:  0.580nMAssay Description:The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloprotease-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Glycomed

Curated by ChEMBL
LigandPNGBDBM50062311((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(R)-1-(3-morphol...)
Affinity DataKi:  0.590nMAssay Description:Binding affinity towards 72 kDa gelatinase (Matrix metalloprotease-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed