BDBM50062433 9-Chloro-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL318409

SMILES CC1=CC(C)(C)Nc2ccc3-c4cc(Cl)ccc4OC(c4ccccc4)c3c12

InChI Key InChIKey=ANIOYQXTAMMUKZ-UHFFFAOYSA-N

Data  5 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50062433   

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062433(9-Chloro-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H-6...)
Affinity DataKi:  0.740nMAssay Description:The binding affinity measured using baculovirus-expressed hPR-A in sf21 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062433(9-Chloro-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H-6...)
Affinity DataKi:  9.30nMAssay Description:Binding affinity for glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062433(9-Chloro-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H-6...)
Affinity DataKi:  53nMAssay Description:Binding affinity for progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMineralocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062433(9-Chloro-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H-6...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity for mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAndrogen receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062433(9-Chloro-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H-6...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity for androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062433(9-Chloro-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H-6...)
Affinity DataEC50:  6.90nMAssay Description:Agonistic activity was measured for modulation of hPR-B (human progesterone receptor) in co-transfected CV-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed