BDBM50062624 (S)-1-(2,3-Dihydro-benzo[1,4]dioxine-2-carbonyl)-pyrrolidine-2-carboxylic acid (4-amino-cyclohexylmethyl)-amide::CHEMBL420689

SMILES NC1CCC(CNC(=O)[C@@H]2CCCN2C(=O)C2COc3ccccc3O2)CC1

InChI Key InChIKey=NDXXIBJDVBVFKU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50062624   

TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50062624((S)-1-(2,3-Dihydro-benzo[1,4]dioxine-2-carbonyl)-p...)
Affinity DataKi:  75nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50062624((S)-1-(2,3-Dihydro-benzo[1,4]dioxine-2-carbonyl)-p...)
Affinity DataIC50: 100nMAssay Description:Inhibition of thrombin-catalyzed hydrolysis of a standard substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed