BDBM50063260 10-(4-methylhexahydro-1-pyrazinyl)-9-azatetracyclo[11.2.1.02,11.03,8]hexadeca-2(11),3,5,7,9-pentaene::6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-8,10-ethanophenanthridine::CHEMBL287987

SMILES CN1CCN(CC1)c1nc2ccccc2c2C3CCC(C3)Cc12

InChI Key InChIKey=SRTWNZVLIRBNGI-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50063260   

Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50063260(6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-8,...)
Affinity DataKi:  0.830nMAssay Description:Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50063260(6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-8,...)
Affinity DataKi:  83nMAssay Description:Ability to displace [3H]granisetron specifically bound to 5-hydroxytryptamine 3 receptor in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50063260(6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-8,...)
Affinity DataKi:  2.30E+3nMAssay Description:Ability to displace [3H]5-HT bound to 5-hydroxytryptamine 1B receptor in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50063260(6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-8,...)
Affinity DataKi:  2.80E+3nMAssay Description:Ability to displace [3H]mesulergine bound to 5-hydroxytryptamine 2C receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50063260(6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-8,...)
Affinity DataKi:  3.70E+3nMAssay Description:Ability to displace [3H]ketanserin bound to 5-hydroxytryptamine 2A receptor in rat pre-frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50063260(6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-8,...)
Affinity DataKi:  2.40E+4nMAssay Description:Ability to displace [3H]- -OH-DPAT bound to 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50063260(6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-8,...)
Affinity DataKi:  2.40E+4nMAssay Description:Ability to displace [3H]paroxetine bound to Serotonin transporter receptor in rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed