BDBM50063906 (S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-1-(furan-2-carbonyl)-piperazine-2-carboxylic acid tert-butylamide::CHEMBL19826
SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN([C@@H](C1)C(=O)NC(C)(C)C)C(=O)c1ccco1
InChI Key InChIKey=XSHSZTXMXLVUME-INIZCTEOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50063906
Affinity DataKi: 3.5nMAssay Description:Compound was tested for binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1B adrenergi...More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 73nMAssay Description:Compound was tested for binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1D adrenergi...More data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 580nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:Compound was tested for binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1A adrenergi...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Compound was tested for the tissue binding affinity using [3H]- Prazosin as radioligand to the rat spleen Alpha-1B adrenergic receptor subtypeMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Compound was tested for the tissue binding affinity using [125I]- HEAT as radioligand to the human aorta Alpha-1B adrenergic receptor subtypeMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Compound was tested for the tissue binding affinity using [3H]- Prazosin as radioligand to the rat prostate Alpha-1A adrenergic receptor subtypeMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Compound was tested for the tissue binding affinity using [125I]- HEAT as radioligand to the human aorta Alpha-1B adrenergic receptor subtypeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Compound was tested for the tissue binding affinity using [3H]- Prazosin as radioligand to the human prostate Alpha-1A adrenergic receptor subtypeMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Compound was tested for the tissue binding affinity using [3H]- Prazosin as radioligand to the rat liver Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair