BDBM50063914 (R)-N*4*-Hydroxy-N*1*-((S)-methylcarbamoyl-phenyl-methyl)-2-phenethyl-succinamide::CHEMBL19623

SMILES CNC(=O)[C@@H](NC(=O)[C@H](CCc1ccccc1)CC(=O)NO)c1ccccc1

InChI Key InChIKey=KEPYRBFIGNMAQF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50063914   

TargetMatrix metalloproteinase-9(Human)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063914((R)-N*4*-Hydroxy-N*1*-((S)-methylcarbamoyl-phenyl-...)
Affinity DataIC50: 11nMAssay Description:Activity against Matrix metalloprotease-9 (MMP-9).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063914((R)-N*4*-Hydroxy-N*1*-((S)-methylcarbamoyl-phenyl-...)
Affinity DataIC50: 17nMAssay Description:Activity against Matrix metalloprotease-3 (MMP-3).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063914((R)-N*4*-Hydroxy-N*1*-((S)-methylcarbamoyl-phenyl-...)
Affinity DataIC50: 46.3nMAssay Description:Activity against Matrix metalloprotease-2 (MMP-2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063914((R)-N*4*-Hydroxy-N*1*-((S)-methylcarbamoyl-phenyl-...)
Affinity DataIC50: 92nMAssay Description:Activity against Matrix metalloprotease-1 (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063914((R)-N*4*-Hydroxy-N*1*-((S)-methylcarbamoyl-phenyl-...)
Affinity DataIC50: 105nMAssay Description:Activity against deletion mutant of MT1-MMP lacking the transmembrane domain (deltaMT1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed