BDBM50063916 (R)-N*4*-Hydroxy-N*1*-((S)-methylcarbamoyl-phenyl-methyl)-2-(3-phenyl-propyl)-succinamide::CHEMBL432842

SMILES CNC(=O)[C@@H](NC(=O)[C@H](CCCc1ccccc1)CC(=O)NO)c1ccccc1

InChI Key InChIKey=YPHZFHQBHSELGO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50063916   

Target72 kDa type IV collagenase(Human)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063916((R)-N*4*-Hydroxy-N*1*-((S)-methylcarbamoyl-phenyl-...)
Affinity DataIC50: 3.20nMAssay Description:Activity against Matrix metalloprotease-2 (MMP-2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063916((R)-N*4*-Hydroxy-N*1*-((S)-methylcarbamoyl-phenyl-...)
Affinity DataIC50: 3.30nMAssay Description:Activity against Matrix metalloprotease-9 (MMP-9).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063916((R)-N*4*-Hydroxy-N*1*-((S)-methylcarbamoyl-phenyl-...)
Affinity DataIC50: 8.5nMAssay Description:Activity against deletion mutant of MT1-MMP lacking the transmembrane domain (deltaMT1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063916((R)-N*4*-Hydroxy-N*1*-((S)-methylcarbamoyl-phenyl-...)
Affinity DataIC50: 9.60nMAssay Description:Activity against Matrix metalloprotease-3 (MMP-3).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063916((R)-N*4*-Hydroxy-N*1*-((S)-methylcarbamoyl-phenyl-...)
Affinity DataIC50: 89nMAssay Description:Activity against Matrix metalloprotease-1 (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed