BDBM50063919 (2R,3R)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-methylcarbamoyl-phenyl-methyl)-3-morpholin-4-ylmethyl-succinamide::CHEMBL433816

SMILES CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](CN1CCOCC1)C(=O)NO)c1ccccc1

InChI Key InChIKey=DYKLASPWVUKEIT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50063919   

TargetInterstitial collagenase(Human)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063919((2R,3R)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-methylca...)
Affinity DataIC50: 3.5nMAssay Description:Activity against Matrix metalloprotease-1 (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063919((2R,3R)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-methylca...)
Affinity DataIC50: 45nMAssay Description:Activity against Matrix metalloprotease-9 (MMP-9).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063919((2R,3R)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-methylca...)
Affinity DataIC50: 61nMAssay Description:Activity against Matrix metalloprotease-3 (MMP-3).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063919((2R,3R)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-methylca...)
Affinity DataIC50: 72nMAssay Description:Activity against deletion mutant of MT1-MMP lacking the transmembrane domain (deltaMT1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed