BDBM50063921 (2R,3S)-N*1*-((S)-Cyclohexyl-methylcarbamoyl-methyl)-N*4*-hydroxy-2-isobutyl-3-methyl-succinamide::CHEMBL19932

SMILES CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](C)C(=O)NO)C1CCCCC1

InChI Key InChIKey=RHWGGEKVTPKRQW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50063921   

TargetMatrix metalloproteinase-9(Human)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063921((2R,3S)-N*1*-((S)-Cyclohexyl-methylcarbamoyl-methy...)
Affinity DataIC50: 0.900nMAssay Description:Activity against Matrix metalloprotease-9 (MMP-9).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063921((2R,3S)-N*1*-((S)-Cyclohexyl-methylcarbamoyl-methy...)
Affinity DataIC50: 2.90nMAssay Description:Activity against Matrix metalloprotease-1 (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063921((2R,3S)-N*1*-((S)-Cyclohexyl-methylcarbamoyl-methy...)
Affinity DataIC50: 13nMAssay Description:Activity against deletion mutant of MT1-MMP lacking the transmembrane domain (deltaMT1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed