BDBM50063981 5-[(3-Methoxy-phenylamino)-methyl]-furo[2,3-d]pyrimidine-2,4-diamine::CHEMBL23658

SMILES COc1cccc(NCc2coc3nc(N)nc(N)c23)c1

InChI Key InChIKey=ZOGWMLAEHZGMOA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50063981   

TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063981(5-[(3-Methoxy-phenylamino)-methyl]-furo[2,3-d]pyri...)
Affinity DataIC50: 3.13E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase from pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063981(5-[(3-Methoxy-phenylamino)-methyl]-furo[2,3-d]pyri...)
Affinity DataIC50: 3.13E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase from Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063981(5-[(3-Methoxy-phenylamino)-methyl]-furo[2,3-d]pyri...)
Affinity DataIC50: 3.13E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed