BDBM50063986 5-[(2-Phenoxy-phenylamino)-methyl]-furo[2,3-d]pyrimidine-2,4-diamine::CHEMBL23353

SMILES Nc1nc(N)c2c(CNc3ccccc3Oc3ccccc3)coc2n1

InChI Key InChIKey=GXOWALMMPBQPIM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50063986   

TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063986(5-[(2-Phenoxy-phenylamino)-methyl]-furo[2,3-d]pyri...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase from pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063986(5-[(2-Phenoxy-phenylamino)-methyl]-furo[2,3-d]pyri...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063986(5-[(2-Phenoxy-phenylamino)-methyl]-furo[2,3-d]pyri...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase from Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed