BDBM50063989 5-(phenylthiomethyl)furo[2,3-d]pyrimidine-2,4-diamine::5-Phenylsulfanylmethyl-furo[2,3-d]pyrimidine-2,4-diamine::CHEMBL22820

SMILES Nc1nc(N)c2c(CSc3ccccc3)coc2n1

InChI Key InChIKey=IDRUEHBEYROHLG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50063989   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063989(5-Phenylsulfanylmethyl-furo[2,3-d]pyrimidine-2,4-d...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase from Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063989(5-Phenylsulfanylmethyl-furo[2,3-d]pyrimidine-2,4-d...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063989(5-Phenylsulfanylmethyl-furo[2,3-d]pyrimidine-2,4-d...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase from pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063989(5-Phenylsulfanylmethyl-furo[2,3-d]pyrimidine-2,4-d...)
Affinity DataIC50: 2.52E+5nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063989(5-Phenylsulfanylmethyl-furo[2,3-d]pyrimidine-2,4-d...)
Affinity DataIC50: 2.52E+5nMAssay Description:Inhibitory activity against dihydrofolate reductase from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed