BDBM50064786 (S)-1-(2-(4-(4-methoxyphenyl)piperazin-1-yl)ethyl)-N-methyl-3,4-dihydro-1H-isochromene-6-carboxamide::(S)-1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid methylamide::CHEMBL71838
SMILES CNC(=O)c1ccc2[C@H](CCN3CCN(CC3)c3ccc(OC)cc3)OCCc2c1
InChI Key InChIKey=UDLSEQDYARNKTL-QHCPKHFHSA-N
Data 13 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50064786
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]5-hydroxytryptamine from human cloned 5HT1D receptor expressed in CHOK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]serotonin from recombinant human 5-HT1D receptor expressed in HEK293 cells incubated for 1 hr by competitive radioligand binding ...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:The compound was tested for CNS binding affinity towards 5-hydroxytryptamine 1D receptor from cloned gorilla membranes expressed in cultured HEK 293 ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Shaanxi University Of Chinese Medicine
Curated by ChEMBL
Shaanxi University Of Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 168nMAssay Description:Displacement of ketanserin from human 5-HT2A receptor expressed in CHO cell membrane incubated for 1 hr by competitive radioligand binding assay base...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Shaanxi University Of Chinese Medicine
Curated by ChEMBL
Shaanxi University Of Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 168nMAssay Description:The compound was tested for CNS binding affinity towards 5-hydroxytryptamine 2A receptor from cloned Human membranesMore data for this Ligand-Target Pair
Affinity DataKi: 241nMAssay Description:The compound was tested for CNS binding affinity towards Dopamine receptor D2 from cloned Human membranes.More data for this Ligand-Target Pair
Affinity DataKi: 241nMAssay Description:Displacement of PNU-86170 from human dopamine D2 receptor expressed in CHO cell membrane incubated for 1 hr by competitive radioligand binding assay ...More data for this Ligand-Target Pair
Affinity DataKi: 1.09E+3nMAssay Description:The compound was tested for CNS binding affinity towards 5-hydroxytryptamine 1A receptor from cloned Human membranes.More data for this Ligand-Target Pair
Affinity DataKi: 1.09E+3nMAssay Description:Displacement of 8-OH-DPAT from human 5-HT1A receptor expressed in CHO cell membrane incubated for 1 hr by competitive radioligand binding assay basedMore data for this Ligand-Target Pair
Affinity DataKi: >3.70E+3nMAssay Description:The compound was tested for CNS binding affinity towards Dopamine receptor D4 from cloned Human membranes.More data for this Ligand-Target Pair
Affinity DataKi: 3.70E+3nMAssay Description:Displacement of spiperone from human dopamine D4 receptor expressed in CHO cell membrane incubated for 1 hr by competitive radioligand binding assay ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Shaanxi University Of Chinese Medicine
Curated by ChEMBL
Shaanxi University Of Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 5.78E+3nMAssay Description:Displacement of [3H]serotonin from recombinant human 5-HT1B receptor expressed in HEK293 cells incubated for 1 hr by competitive radioligand binding ...More data for this Ligand-Target Pair
Affinity DataKi: 5.78E+3nMAssay Description:The compound was tested for CNS binding affinity towards 5-hydroxytryptamine 1B receptor from cloned gorilla membranes expressed in cultured HEK 293 ...More data for this Ligand-Target Pair