BDBM50065118 CHEMBL311931::N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-10-carbonyl)-3-chloro-phenyl]-2,3-dimethyl-benzamide

SMILES Cc1cccc(C(=O)Nc2ccc(C(=O)N3Cc4cccn4Cc4ccccc34)c(Cl)c2)c1C

InChI Key InChIKey=DRCJSVOKCHFWFD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50065118   

TargetVasopressin V2 receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50065118(N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-...)
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]AVP from human V2 receptor expressed in murine fibroblast cell line (LV2) membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50065118(N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-...)
Affinity DataIC50: 430nMAssay Description:Displacement of [3H]AVP from vasopressin receptor (V1a) from human platelet membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed