BDBM50066280 CHEMBL2419122

SMILES O=C(N[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@H]1O5)c1nc(Cl)c2ccccc2c1O

InChI Key InChIKey=XUFUXQCDCPXCAO-UHFFFAOYSA-N

Data  6 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50066280   

TargetMu-type opioid receptor(Mouse)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066280BDBM50066280(CHEMBL2419122)
Affinity DataKi:  0.730nMAssay Description:Displacement of [3H]naloxane from mouse MOR expressed in CHO cells after 1.5 hrs by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066280BDBM50066280(CHEMBL2419122)
Affinity DataKi:  0.730nMAssay Description:Displacement of [3H]-naloxone from mouse mu opioid receptor expressed in CHO cells after 1.5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066280BDBM50066280(CHEMBL2419122)
Affinity DataEC50:  1.20nMAssay Description:Stimulation of mouse MOR expressed in CHO cells after 1.5 hrs by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066280BDBM50066280(CHEMBL2419122)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at mouse mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]-GTPgammaS binding after 1.5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066280BDBM50066280(CHEMBL2419122)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]naltrindole from mouse DOR expressed in CHO cells after 1.5 hrs by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066280BDBM50066280(CHEMBL2419122)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-naltrindole from mouse delta opioid receptor expressed in CHO cells after 1.5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066280BDBM50066280(CHEMBL2419122)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]diprenorphine from mouse KOR expressed in CHO cells after 1.5 hrs by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066280BDBM50066280(CHEMBL2419122)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-diprenorphine from mouse kappa opioid receptor expressed in CHO cells after 1.5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed