BDBM50067280 CHEMBL542958::N-({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-3-pyridin-3-yl-acrylamide ; dihydrochloride

SMILES CN(C(=O)CNC(=O)\C=C\c1cccnc1)c1ccc(Cl)c(COc2cccc3ccc(C)nc23)c1Cl

InChI Key InChIKey=LPYVASFSWSGEFU-UKTHLTGXSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50067280   

TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067280(CHEMBL542958 | N-({[2,4-Dichloro-3-(2-methyl-quino...)
Affinity DataIC50:  0.790nMAssay Description:Concentration required to inhibit specific binding of [ 3H]BK (0.06 nM) to Bradykinin receptor B2 in guinea pig ileum membrane preparations by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetB2 bradykinin receptor(Guinea pig)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067280(CHEMBL542958 | N-({[2,4-Dichloro-3-(2-methyl-quino...)
Affinity DataIC50:  0.790nMAssay Description:Concentration required to inhibit specific binding of [ 3H]BK (0.06 nM) to Bradykinin receptor B2 in guinea pig ileum membrane preparations by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed