BDBM50068233 CHEMBL1580288

SMILES CCS(=O)(=O)c1nc(c(s1)N1CCc2ccccc2C1)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=XWBNXNPYMCYTKF-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50068233   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50068233(CHEMBL1580288)
Affinity DataKi:  119nMAssay Description:Binding affinity to 5-HT6R (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50068233(CHEMBL1580288)
Affinity DataKi:  119nMAssay Description:Displacement of [3H]LSD from human cloned 5-HT6R expressed in HEK293 cells using seven compounds concentrationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50068233(CHEMBL1580288)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]LSD from human cloned 5-HT6R expressed in HEK293 cells at 0.1 and 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50068233(CHEMBL1580288)
Affinity DataKi:  296nMAssay Description:Displacement of [3H]-ketanserin from human cloned 5-HT2A receptor expressed in CHO-K1 cells using seven compounds concentrationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50068233(CHEMBL1580288)
Affinity DataKi:  315nMAssay Description:Displacement of [3H]-ketanserin from human cloned 5-HT2A receptor expressed in CHO-K1 cells at 0.1 and 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50068233(CHEMBL1580288)
Affinity DataKi:  1.22E+4nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5-HT1A receptor expressed in HEK293 cells at 0.1 and 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50068233(CHEMBL1580288)
Affinity DataKi:  1.58E+4nMAssay Description:Displacement of [3H]-5-CT from human cloned 5-HT7R expressed in HEK293 cells at 0.1 and 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed