BDBM50068533 3-Benzyl-8-[4-(4-fluoro-phenyl)-4-oxo-butyl]-1-methyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL146569

SMILES CN1CN(Cc2ccccc2)C(=O)C11CCN(CCCC(=O)c2ccc(F)cc2)CC1

InChI Key InChIKey=YKAOMUQLWWJOBI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50068533   

Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50068533(3-Benzyl-8-[4-(4-fluoro-phenyl)-4-oxo-butyl]-1-met...)
Affinity DataKi:  22nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2A receptor in NIH3T3 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50068533(3-Benzyl-8-[4-(4-fluoro-phenyl)-4-oxo-butyl]-1-met...)
Affinity DataKi:  265nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 1A receptor in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50068533(3-Benzyl-8-[4-(4-fluoro-phenyl)-4-oxo-butyl]-1-met...)
Affinity DataKi:  1.41E+3nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2C receptor in A-9 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed