BDBM50069097 CHEMBL3403518::US10189853, Compound 11
SMILES CC(C)Oc1ccc(cc1)N(C)c1nc(C)nc2oc(C)cc12
InChI Key InChIKey=NTMALOHZZAUBAI-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50069097
Affinity DataIC50: 102nMAssay Description:Inhibition of EGFR in human A431 cells compound pretreated for 60 min before EGF stimulation for 10 mins by phosphotyrosine ELISA cytoblot methodMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of VEGFR2 in human U251 cells compound pretreated for 60 min before VEGF stimulation for 10 mins by phosphotyrosine ELISA cytoblot methodMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Human)
Duquesne University of The Holy Spirit
US Patent
Duquesne University of The Holy Spirit
US Patent
Affinity DataIC50: 84nMAssay Description:RTK inhibitory activity of the compounds 2-12 were evaluated using human tumor cells known to express high levels of EGFR, VEGFR-2 or PDFGR-β us...More data for this Ligand-Target Pair
Affinity DataIC50: 102nMAssay Description:RTK inhibitory activity of the compounds 2-12 were evaluated using human tumor cells known to express high levels of EGFR, VEGFR-2 or PDFGR-β us...More data for this Ligand-Target Pair
Affinity DataIC50: 38.5nMAssay Description:RTK inhibitory activity of the compounds 2-12 were evaluated using human tumor cells known to express high levels of EGFR, VEGFR-2 or PDFGR-β us...More data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of PDGFR-beta in human U251 cells compound pretreated for 60 min before PDGF-BB stimulation for 10 mins by phosphotyrosine ELISA cytoblot ...More data for this Ligand-Target Pair