BDBM50069626 CHEMBL3402515

SMILES CC(C)C1=C(SC2=N[C@](C)([C@H](N12)c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(=O)N1[C@H](C)CC[C@H]1C(=O)N1CCN(C)C2(CC2)C1

InChI Key InChIKey=ZCAFJDRQRAWKAO-GRZVAKJNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069626   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50069626(CHEMBL3402515)
Affinity DataIC50:  21nMAssay Description:Binding affinity to GST-tagged MDM2 (unknown origin) assessed as inhibition of interaction with His-tagged p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed