BDBM50069627 CHEMBL3402516

SMILES CC(C)C1=C(SC2=N[C@](C)([C@H](N12)c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(=O)N1[C@H](C)CC[C@H]1C(=O)N1CCNC2(CC2)C1

InChI Key InChIKey=XLBQSMBISPUIMT-MAMXRPNDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069627   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50069627(CHEMBL3402516)
Affinity DataIC50:  9.5nMAssay Description:Binding affinity to GST-tagged MDM2 (unknown origin) assessed as inhibition of interaction with His-tagged p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed