BDBM50069751 CHEMBL2356114

SMILES C[C@@H](N(C1CCCCC1)C(=O)Cn1nnc(n1)-c1ccc2OCOc2c1)C(=O)NC1CCCC1

InChI Key InChIKey=RZNBRWZQSTXMIV-MRXNPFEDSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50069751   

TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50069751(CHEMBL2356114)
Affinity DataIC50:  5nMAssay Description:Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of [3H]cholesteryl ester uptake into cells after 2 to 3 hrs by liquid sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50069751(CHEMBL2356114)
Affinity DataEC50:  270nMAssay Description:Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as increase in binding of Alexa-488-labeled HDL particles to cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50069751(CHEMBL2356114)
Affinity DataIC50:  17nMAssay Description:Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50069751(CHEMBL2356114)
Affinity DataIC50:  5nMAssay Description:Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in uptake of [3H]CE from [3H]CE-HDL by by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed