BDBM50069908 CHEMBL102490::N-(2-Chloro-5-{2-[(thiophen-2-ylmethyl)-amino]-ethoxy}-phenyl)-methanesulfonamide

SMILES CS(=O)(=O)Nc1cc(OCCNCc2cccs2)ccc1Cl

InChI Key InChIKey=RGVJFPMOLSXLGJ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50069908   

TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069908(N-(2-Chloro-5-{2-[(thiophen-2-ylmethyl)-amino]-eth...)
Affinity DataKi:  2.60nMAssay Description:Antagonistic activity towards dopamine D2 receptor using radioligand [3H]spiperone in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069908(N-(2-Chloro-5-{2-[(thiophen-2-ylmethyl)-amino]-eth...)
Affinity DataKi:  6nMAssay Description:Antagonistic activity towards dopamine D2 receptor using radioligand [3H]spiperone in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069908(N-(2-Chloro-5-{2-[(thiophen-2-ylmethyl)-amino]-eth...)
Affinity DataKi:  9nMAssay Description:Binding affinity towards human cloned dopamine (hD2s) receptors expressed in CHO cell membranes using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069908(N-(2-Chloro-5-{2-[(thiophen-2-ylmethyl)-amino]-eth...)
Affinity DataKi:  28nMAssay Description:Binding affinity towards human cloned dopamine (hD3) receptor expressed in CHO cells using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069908(N-(2-Chloro-5-{2-[(thiophen-2-ylmethyl)-amino]-eth...)
Affinity DataKi:  137nMAssay Description:Binding affinity towards human cloned dopamine (hD4.4) receptor expressed in CHO cells using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed