BDBM50070354 8-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperidin-3-yl]-propyl}-3-phenyl-2,3,8-triaza-spiro[4.5]decan-1-one::CHEMBL26951

SMILES Clc1ccc(cc1Cl)C1(CCCN2CCC3(CN(NC3=O)c3ccccc3)CC2)CCCN(C1)C(=O)c1ccccc1

InChI Key InChIKey=HPPQGIFLKZFURI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50070354   

TargetNeuromedin-K receptor(Human)
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070354(8-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperidin-...)
Affinity DataIC50: 6.80nMAssay Description:Compound was evaluated for its ability to displace [3H]NKB binding in hNK3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070354(8-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperidin-...)
Affinity DataIC50: 50nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070354(8-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperidin-...)
Affinity DataIC50: 108nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed