BDBM50072095 CHEMBL3407877

SMILES OC(=O)c1ncnc(c1F)-c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=JDAHHGAIIWSSEX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072095   

TargetKynurenine 3-monooxygenase(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072095(CHEMBL3407877)
Affinity DataIC50: 6nMAssay Description:Inhibition of human KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072095(CHEMBL3407877)
Affinity DataIC50: 6nMAssay Description:Inhibition of human KMOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072095(CHEMBL3407877)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of human KMO transfected in CHO cells assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed