BDBM50074223 6-Ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propyl-nicotinic acid 3-fluoro-propyl ester::CHEMBL422184

SMILES CCCc1c(C(=O)SCC)c(CC)nc(-c2ccccc2)c1C(=O)OCCCF

InChI Key InChIKey=PCKXPIQJKLNHMF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50074223   

TargetAdenosine receptor A3(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50074223(6-Ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propyl-...)
Affinity DataKi:  9.67nMAssay Description:Displacement of specific [125 I]AB-MECA binding at human Adenosine A3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50074223(6-Ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propyl-...)
Affinity DataKi:  512nMAssay Description:Displacement of specific [125I]AB-MECA binding at rat Adenosine A3 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50074223(6-Ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propyl-...)
Affinity DataKi:  6.05E+3nMAssay Description:Displacement of specific [3H]-CGS- 21680R-PIA binding to Adenosine A1 receptor in rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50074223(6-Ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propyl-...)
Affinity DataKi:  9.67E+3nMAssay Description:Inhibition of [3H]-CGS- 21680 binding to Adenosine A2A receptor in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed