BDBM50074277 CHEMBL25412::US20260008771, Name MW041::[2-(1-Benzyl-piperidin-4-yl)-ethyl]-(6-phenyl-pyridazin-3-yl)-amine; dihydrochloride; Hydrate::[2-(1-Benzyl-piperidin-4-yl)-ethyl]-(6-phenyl-pyridazin-3-yl)-amine; hydrochloride

SMILES C(CC1CCN(Cc2ccccc2)CC1)Nc1ccc(nn1)-c1ccccc1

InChI Key InChIKey=PHORSJQGLQBIOY-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50074277   

TargetAcetylcholinesterase(Electric eel)
Prestwick Chemical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074277BDBM50074277(CHEMBL25412 | [2-(1-Benzyl-piperidin-4-yl)-ethyl]-...)
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration towards acetylcholinesterase in electric eelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
Louis Pasteur University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074277BDBM50074277(CHEMBL25412 | [2-(1-Benzyl-piperidin-4-yl)-ethyl]-...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibition of Torpedo californica acetylcholinesterase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074277BDBM50074277(CHEMBL25412 | [2-(1-Benzyl-piperidin-4-yl)-ethyl]-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Prestwick Chemical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074277BDBM50074277(CHEMBL25412 | [2-(1-Benzyl-piperidin-4-yl)-ethyl]-...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibition of electric eel acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074277BDBM50074277(CHEMBL25412 | [2-(1-Benzyl-piperidin-4-yl)-ethyl]-...)
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration against acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074277BDBM50074277(CHEMBL25412 | [2-(1-Benzyl-piperidin-4-yl)-ethyl]-...)
Affinity DataIC50: 140nMAssay Description:In vitro inhibition of acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Columbia University

US Patent
LigandChemical structure of BindingDB Monomer ID 50074277BDBM50074277(CHEMBL25412 | [2-(1-Benzyl-piperidin-4-yl)-ethyl]-...)
Affinity DataIC50: 450nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

TargetCholinesterase(Human)
Louis Pasteur University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074277BDBM50074277(CHEMBL25412 | [2-(1-Benzyl-piperidin-4-yl)-ethyl]-...)
Affinity DataIC50: 700nMAssay Description:Inhibition of butyrylcholinesterase from human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Louis Pasteur University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074277BDBM50074277(CHEMBL25412 | [2-(1-Benzyl-piperidin-4-yl)-ethyl]-...)
Affinity DataIC50: 700nMAssay Description:Inhibitory concentration against Butyrylcholinesterase (BuChE) from human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed