BDBM50074684 CHEMBL442133::[7,2-bis{(4-Oxo-butoxy)-thr-leu-asp-phe-oMe}]-pyridinyl:trihydrate

SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)CCCOc1cccc(OCCCC(=O)N[C@@H](C(C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)OC)n1)C(C)O

InChI Key InChIKey=FRSAXEPCYIKYSK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074684   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Université

Curated by ChEMBL
LigandPNGBDBM50074684([7,2-bis{(4-Oxo-butoxy)-thr-leu-asp-phe-oMe}]-pyri...)
Affinity DataIC50: 1.00E+4nMAssay Description:The compound was tested for HIV-1 protease inhibitory activity against plasmid pET9c-PR expressing HIV-1 protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed