BDBM50074686 4-[7,2-bis{(4-Oxo-butoxy)-thr-leu-asp-phe-OMe]-naphthalenyl:dihydrate::CHEMBL415804

SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)CCCOc1ccc2ccc(OCCCC(=O)N[C@@H](C(C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc3ccccc3)C(=O)OC)cc2c1)C(C)O

InChI Key InChIKey=OJAMQELHKWDHFU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074686   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Université

Curated by ChEMBL
LigandPNGBDBM50074686(4-[7,2-bis{(4-Oxo-butoxy)-thr-leu-asp-phe-OMe]-nap...)
Affinity DataIC50: 4.40E+3nMAssay Description:The compound was tested for HIV-1 protease inhibitory activity against plasmid pET9c-PR expressing HIV-1 protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed