BDBM50074718 6-(3-Methoxy-benzyl)-5,6,7,8-tetrahydro-quinazoline-2,4-diamine::6-(3-methoxybenzyl)-5,6,7,8-tetrahydroquinazoline-2,4-diamine::CHEMBL268355

SMILES COc1cccc(CC2CCc3nc(N)nc(N)c3C2)c1

InChI Key InChIKey=CMALOCWWCHGZIN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074718   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074718(6-(3-methoxybenzyl)-5,6,7,8-tetrahydroquinazoline-...)
Affinity DataIC50: 21nMAssay Description:The ability to inhibit Toxoplasma gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074718(6-(3-methoxybenzyl)-5,6,7,8-tetrahydroquinazoline-...)
Affinity DataIC50: 110nMAssay Description:The ability to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074718(6-(3-methoxybenzyl)-5,6,7,8-tetrahydroquinazoline-...)
Affinity DataIC50: 270nMAssay Description:The ability to inhibit Pneumocystis carinii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed