BDBM50074725 6-tert-Butyl-5,6,7,8-tetrahydro-quinazoline-2,4-diamine::6-tert-butyl-5,6,7,8-tetrahydroquinazoline-2,4-diamine::CHEMBL7571

SMILES CC(C)(C)C1CCc2nc(N)nc(N)c2C1

InChI Key InChIKey=ZNQWFSHAFZBMJV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074725   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074725(6-tert-butyl-5,6,7,8-tetrahydroquinazoline-2,4-dia...)
Affinity DataIC50: 18nMAssay Description:The ability to inhibit Toxoplasma gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074725(6-tert-butyl-5,6,7,8-tetrahydroquinazoline-2,4-dia...)
Affinity DataIC50: 65nMAssay Description:The ability to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074725(6-tert-butyl-5,6,7,8-tetrahydroquinazoline-2,4-dia...)
Affinity DataIC50: 180nMAssay Description:The ability to inhibit Pneumocystis carinii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed