BDBM50074726 6-(4-(trifluoromethoxy)benzyl)-5,6,7,8-tetrahydroquinazoline-2,4-diamine::6-(4-Trifluoromethoxy-benzyl)-5,6,7,8-tetrahydro-quinazoline-2,4-diamine::CHEMBL7062

SMILES Nc1nc(N)c2CC(Cc3ccc(OC(F)(F)F)cc3)CCc2n1

InChI Key InChIKey=XWYNMTCVJRLFSS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074726   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074726(6-(4-Trifluoromethoxy-benzyl)-5,6,7,8-tetrahydro-q...)
Affinity DataIC50: 73nMAssay Description:The ability to inhibit Toxoplasma gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074726(6-(4-Trifluoromethoxy-benzyl)-5,6,7,8-tetrahydro-q...)
Affinity DataIC50: 170nMAssay Description:The ability to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074726(6-(4-Trifluoromethoxy-benzyl)-5,6,7,8-tetrahydro-q...)
Affinity DataIC50: 580nMAssay Description:The ability to inhibit Pneumocystis carinii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed