BDBM50075352 4-[8-(4-Chloro-phenyl)-5,5-dimethyl-5,6-dihydro-naphthalen-2-ylethynyl]-benzoic acid::CHEMBL157160

SMILES CC1(C)CC=C(c2ccc(Cl)cc2)c2cc(ccc12)C#Cc1ccc(cc1)C(O)=O

InChI Key InChIKey=KVOZBEGIILRVTE-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075352   

TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50075352(4-[8-(4-Chloro-phenyl)-5,5-dimethyl-5,6-dihydro-na...)
Affinity DataKd:  27nMAssay Description:Ability to displace 3[H]-(all-E)-retinoic acid (5 nM) from Retinoic acid receptor gamma using transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRetinoic acid receptor beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50075352(4-[8-(4-Chloro-phenyl)-5,5-dimethyl-5,6-dihydro-na...)
Affinity DataKd:  18nMAssay Description:Ability to displace 3[H]-(all-E)-retinoic acid (5 nM) from beta retinoic acid receptor (beta RAR) using transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRetinoic acid receptor alpha(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50075352(4-[8-(4-Chloro-phenyl)-5,5-dimethyl-5,6-dihydro-na...)
Affinity DataKd:  58nMAssay Description:Ability to displace 3[H]-(all-E)-retinoic acid (5 nM) from alpha retinoic acid receptor (alpha RAR) using transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed