BDBM50075354 4-(5,5-Dimethyl-8-m-tolyl-5,6-dihydro-naphthalen-2-ylethynyl)-benzoic acid::CHEMBL153974

SMILES Cc1cccc(c1)C1=CCC(C)(C)c2ccc(cc12)C#Cc1ccc(cc1)C(O)=O

InChI Key InChIKey=JOGOTUBKFULAEK-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075354   

TargetRetinoic acid receptor beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50075354(4-(5,5-Dimethyl-8-m-tolyl-5,6-dihydro-naphthalen-2...)
Affinity DataKd:  51nMAssay Description:Ability to displace 3[H](all-E)-retinoic acid (5 nM) from beta retinoic acid receptor (beta RAR) using transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50075354(4-(5,5-Dimethyl-8-m-tolyl-5,6-dihydro-naphthalen-2...)
Affinity DataKd:  67nMAssay Description:Ability to displace 3[H](all-E)-retinoic acid (5 nM) from Retinoic acid receptor gamma using transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50075354(4-(5,5-Dimethyl-8-m-tolyl-5,6-dihydro-naphthalen-2...)
Affinity DataKd:  276nMAssay Description:Ability to displace 3[H](all-E)-retinoic acid (5 nM) from alpha retinoic acid receptor (alpha RAR) using transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed