BDBM50075427 1-Benzyl-4-(4-methoxy-phenyl)-2-oxo-1,2-dihydro-benzo[4,5]furo[3,2-b]pyridine-3-carboxylic acid::CHEMBL345380

SMILES COc1ccc(cc1)-c1c(C(O)=O)c(=O)n(Cc2ccccc2)c2c1oc1ccccc21

InChI Key InChIKey=OVOHLYDLNHSOEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50075427   

TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50075427(1-Benzyl-4-(4-methoxy-phenyl)-2-oxo-1,2-dihydro-be...)
Affinity DataIC50: 2.70E+3nMAssay Description:Ability to displace [125I]endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50075427(1-Benzyl-4-(4-methoxy-phenyl)-2-oxo-1,2-dihydro-be...)
Affinity DataIC50: 3.00E+3nMAssay Description:Ability to displace [125I]endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed